Search results for "transfer learning"
showing 10 items of 10 documents
Improving Small Molecule pKa Prediction Using Transfer Learning With Graph Neural Networks
2022
Enumerating protonation states and calculating microstate pKa values of small molecules is an important yet challenging task for lead optimization and molecular modeling. Commercial and non-commercial solutions have notable limitations such as restrictive and expensive licenses, high CPU/GPU hour requirements, or the need for expert knowledge to set up and use. We present a graph neural network model that is trained on 714,906 calculated microstate pKa predictions from molecules obtained from the ChEMBL database. The model is fine-tuned on a set of 5,994 experimental pKa values significantly improving its performance on two challenging test sets. Combining the graph neural network model wit…
Deep Generative Model-Driven Multimodal Prostate Segmentation in Radiotherapy
2019
Deep learning has shown unprecedented success in a variety of applications, such as computer vision and medical image analysis. However, there is still potential to improve segmentation in multimodal images by embedding prior knowledge via learning-based shape modeling and registration to learn the modality invariant anatomical structure of organs. For example, in radiotherapy automatic prostate segmentation is essential in prostate cancer diagnosis, therapy, and post-therapy assessment from T2-weighted MR or CT images. In this paper, we present a fully automatic deep generative model-driven multimodal prostate segmentation method using convolutional neural network (DGMNet). The novelty of …
Color and multispectral image processing for the detection of inflammatory lesions of the stomach
2019
The work presented in this manuscript is part of the ANR project EMMIE. This project aims to develop an innovative multimodal system for the detection of inflammatory lesions in the stomach. To this purpose, a prototype has been developed to be able to acquire NBI endoscopic images and multispectral images during human's antrum exploration. The prototype is made of a standard endoscope and multispectral images.The prototype can acquire two types of data: NBI images and spectra. These two modalities are processed independently. Common image processing features are used to recognize four kind of diseases: active gastritis, chronic gastritis, metaplasia and atrophy. In addition, visual based f…
An attention-based weakly supervised framework for spitzoid melanocytic lesion diagnosis in whole slide images
2021
[EN] Melanoma is an aggressive neoplasm responsible for the majority of deaths from skin cancer. Specifically, spitzoid melanocytic tumors are one of the most challenging melanocytic lesions due to their ambiguous morphological features. The gold standard for its diagnosis and prognosis is the analysis of skin biopsies. In this process, dermatopathologists visualize skin histology slides under a microscope, in a highly time-consuming and subjective task. In the last years, computer-aided diagnosis (CAD) systems have emerged as a promising tool that could support pathologists in daily clinical practice. Nevertheless, no automatic CAD systems have yet been proposed for the analysis of spitzoi…
RNN- and LSTM-Based Soft Sensors Transferability for an Industrial Process
2021
The design and application of Soft Sensors (SSs) in the process industry is a growing research field, which needs to mediate problems of model accuracy with data availability and computational complexity. Black-box machine learning (ML) methods are often used as an efficient tool to implement SSs. Many efforts are, however, required to properly select input variables, model class, model order and the needed hyperparameters. The aim of this work was to investigate the possibility to transfer the knowledge acquired in the design of a SS for a given process to a similar one. This has been approached as a transfer learning problem from a source to a target domain. The implementation of a transf…
A Deep Learning Model for Automatic Sleep Scoring using Multimodality Time Series
2021
Sleep scoring is a fundamental but time-consuming process in any sleep laboratory. Automatic sleep scoring is crucial and urgent to help address the increasing unmet need for sleep research. Therefore, this paper aims to develop an end-to-end deep learning architecture using raw polysomnographic recordings to automate sleep scoring. The proposed model adopts two-dimensional convolutional neural networks (2D-CNN) to automatically learn features from multi-modality signals, together with a "squeeze and excitation" block for recalibrating channel-wise feature responses. The learnt representations are finally fed to a softmax classifier to generate predictions for each sleep stage. The model pe…
Recommending Serendipitous Items using Transfer Learning
2018
Most recommender algorithms are designed to suggest relevant items, but suggesting these items does not always result in user satisfaction. Therefore, the efforts in recommender systems recently shifted towards serendipity, but generating serendipitous recommendations is difficult due to the lack of training data. To the best of our knowledge, there are many large datasets containing relevance scores (relevance oriented) and only one publicly available dataset containing a relatively small number of serendipity scores (serendipity oriented). This limits the learning capabilities of serendipity oriented algorithms. Therefore, in the absence of any known deep learning algorithms for recommend…
Transfer Learning of Deep Learning Models for Cloud Masking in Optical Satellite Images
2023
Los satélites de observación de la Tierra proporcionan una oportunidad sin precedentes para monitorizar nuestro planeta a alta resolución tanto espacial como temporal. Sin embargo, para procesar toda esta cantidad creciente de datos, necesitamos desarrollar modelos rápidos y precisos adaptados a las características específicas de los datos de cada sensor. Para los sensores ópticos, detectar las nubes en la imagen es un primer paso inevitable en la mayoría de aplicaciones tanto terrestres como oceánicas. Aunque detectar nubes brillantes y opacas es relativamente fácil, identificar automáticamente nubes delgadas semitransparentes o diferenciar nubes de nieve o superficies brillantes es mucho …
Optimization and sensitivity analysis of existing deep learning models for pavement surface monitoring using low-quality images
2022
Automated pavement distress detection systems have become increasingly sought after by road agencies to in crease the efficiency of field surveys and reduce the likelihood of insufficient road condition data. However, many modern approaches are developed without practical testing using real-world scenarios. This paper ad dresses this by practically analyzing Deep Learning models to detect pavement distresses using French Secondary road surface images, given the issues of limited available road condition data in those networks. The study specifically explores several experimental and sensitivity-testing strategies using augmentation and hyper- parameter case studies to bolster practical mode…
Machine learning at the interface of structural health monitoring and non-destructive evaluation
2020
While both non-destructive evaluation (NDE) and structural health monitoring (SHM) share the objective of damage detection and identification in structures, they are distinct in many respects. This paper will discuss the differences and commonalities and consider ultrasonic/guided-wave inspection as a technology at the interface of the two methodologies. It will discuss how data-based/machine learning analysis provides a powerful approach to ultrasonic NDE/SHM in terms of the available algorithms, and more generally, how different techniques can accommodate the very substantial quantities of data that are provided by modern monitoring campaigns. Several machine learning methods will be illu…